Blakeist

ChatMD: The Convergence of Continuous Health

Jan 7, 2026

Three signals point to a future where health becomes continuous: ChatGPT Health as a daily interface, SleepFM predicting disease from sleep patterns, and AI systems taking bounded clinical actions. The loop is closing.

If You Give an AI a Computer

Jan 1, 2026

When AI gains access to both people affordances and machine affordances, it doesn't just add capabilities—it multiplies them. This is the future of knowledge work.

The Substrate Revolution: When We Mistook the Shadow for the Fire

Dec 27, 2025

Here's what's actually shocking about GLP-1s: they work by making the entire behavioral apparatus of weight loss obsolete. AI does the exact same violence to our model of intelligence.

2026: When the System Becomes the Bottleneck

Dec 26, 2025

The limiting factor shifts from cognition to governance and economics. The model is no longer the bottleneck. The system is.

Speak / See

Dec 17, 2025

Why the future of human-machine interface is already wired to our biology. Yet, we keep installing it backwards

The AI Reflex

Dec 12, 2025

People cannot see their own transformation.

Compound Calibration Part II: The Harness Layer

Dec 9, 2025

Every week brings a new model release. Gemini 3 dropped in mid-November, GPT-5.1 days earlier. Opus 4.5 arrived late November. DeepSeek and Grok and Mistral in the mix. The discourse is endless: which

The Hidden Physics of Work

Nov 28, 2025

Most advice about work describes how work should behave, not how it does.

On the Discipline Problem

Nov 27, 2025

Experienced developers are getting slower with AI tools, not faster. Nineteen percent slower, according to . The juniors are speeding up. The experts are drowning.

We're Eighty Years Early

Nov 25, 2025

I stood in front of Man Ray's rayographs at the MoMA this fall, studying the ghostly white silhouettes floating against dark backgrounds. A glass funnel, a coil of wire, objects I couldn't quite ident

The Fridge Is a Trap

Nov 9, 2025

TradTech opens the fridge and asks what can we make with what we have?

Start With What Models Can Do

Oct 31, 2025

Every company is building an AI strategy by asking, "What can we add?"

The worst time to solve a problem is after you've already solved it

Oct 23, 2025

Pharma marketing has spent two decades optimizing the wrong bottleneck.

AI's Trillion-Dollar Trap

Oct 18, 2025

ChatGPT hit one billion users in three years. The internet took thirty-six.

Compound Calibration

Sep 30, 2025

Your context engineering isn't an implementation detail. It's the whole product. Most AI products feel like wrappers because their prompts, retrieval, and evals deliver basic capability. The ones that

© 2026 Blake Graham

RSS